English  |  正體中文  |  简体中文  |  Items with full text/Total items : 6480/11652
Visitors : 20256345      Online Users : 304
RC Version 3.2 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Adv. Search
LoginUploadHelpAboutAdminister

Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/10096

Title: Chain-Breaking Activity of Carotenes in Lipid Peroxidation: A Theoretical Study
Authors: Guo, Jian-Jhih;Hsieh, Hong-Yi;Hu, Ching-Han
Contributors: 化學系
Date: 2009-11
Issue Date: 2012-05-03T06:18:11Z
Publisher: American Chemical Society
Abstract: Chain-breaking reactions against lipid peroxidation performed by carotenes, including β-carotene (β-CAR) and lycopene (LYC), have been studied using density functional theory. We chose linoleic acid (LAH) as the lipid model and examined two mechanisms: hydrogen abstraction and addition. Our computed reaction diagrams reveal that the addition mechanism is able to offer a larger extent of chain-breaking protection than hydrogen abstraction. In the case of hydrogen abstraction, the resulting carotene radical CAR(−H)• has a smaller O2 affinity than the linoleic acid radical (LA•). Formation of the addition adduct radical ROO−CAR• is energetically favorable, and it has an even smaller tendency to react with O2 than CAR(−H)•. Comparatively, ROO−β-CAR• is less likely to react with O2 than ROO−LYC•. Both the hydrogen abstraction and addition radicals (CAR(−H)• and ROO−CAR•) react readily with a second ROO• radical via either hydrogen abstraction or addition.
Relation: J. Phys. Chem. B, 113(47): 15699-15708
Appears in Collections:[化學系] 期刊論文

Files in This Item:

File SizeFormat
index.html0KbHTML468View/Open


All items in NCUEIR are protected by copyright, with all rights reserved.

 


DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback