English  |  正體中文  |  简体中文  |  Items with full text/Total items : 6491/11663
Visitors : 24492711      Online Users : 65
RC Version 3.2 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Adv. Search
LoginUploadHelpAboutAdminister

Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/11483

Title: Hb Siriraj: a G→A Substitution at Codon 7 of the Beta-globin Chain Creates an MboII Cutting Site
Authors: Chang, J. G.;Yang, T. Y.;Perng, L. I.;Wang, Nancy M.;Peng, C. T.;Tsai, C. H.
Contributors: 生物技術研究所
Date: 1999-05
Issue Date: 2012-06-06T02:03:15Z
Abstract: Nesidioblastosis as the cause of hyperinsulinaemic hypoglycaemia in an adult is rare. We report here an additional case of nesidioblastosis, which resulted in fatal hyperinsulinaemic hypoglycaemia in a 72-year-old woman with an underlying myelodysplastic syndrome. The diagnosis of nesidioblastosis was established only after post-mortem examination with a careful exclusion of minute insulinoma. To our surprise, the renal pathology disclosed typical diabetic nodular glomerulosclerosis in the same patient who had no previous history of diabetes mellitus (DM). Nesidioblastosis has been reported to cause 'reversal' of Type 1 DM and insulinoma causing 'reversal' of Type 2 disease. We therefore hypothesize that our patient might have had an undiagnosed DM in the past, which resulted in the typical diabetic nodular glomerulosclerosis. The nesidioblastosis caused a 'reversal' of DM and even the ultimate development of hyperinsulinaemic hypoglycaemia.
Relation: Hemoglobin, 23(2): 197-199
Appears in Collections:[生物技術研究所] 期刊論文

Files in This Item:

File SizeFormat
2020700310024.pdf47KbAdobe PDF641View/Open


All items in NCUEIR are protected by copyright, with all rights reserved.

 


DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback