National Changhua University of Education Institutional Repository : Item 987654321/11493
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 6507/11669
造访人次 : 30019884      在线人数 : 335
RC Version 3.2 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 进阶搜寻

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.ncue.edu.tw/ir/handle/987654321/11493

题名: P53 Codon 72Arg Polymorphism is Not a Risk Factor for Carcinogenesis in the Chinese
作者: Wang, Nancy M.;Tsai, C. H.;Yeh, K. T.;Chen, S. J.;Chang, J. G.
贡献者: 生物技術研究所
日期: 1999-09
上传时间: 2012-06-06T02:03:30Z
出版者: Spandidos Publications Ltd.
摘要: The potential association of distinct polymorphism of the tumor suppressor gene p53, with an increased susceptibility to malignant transformation has been reported for various cancers. A polymorphism at codon 72 of p53 results in translation to either arginine (p53Arg) or proline (p53Pro), and recent study showed that Caucasian women with arginine form of p53 are more susceptible to HPV-associated carcinoma of the cervix. To examine whether arginine 72 could be a significant risk factor for tumor development, we used a PCR-based assay to analyze p53 genotypes of patients for several types of carcinoma. No significant difference in the frequency of p53Arg was found between normal and cancer patients, the results showed that the individuals homozygous for arginine variant were not at increased risk for cancer.
關聯: Int. J. Mol. Med., 4(3): 249-252
显示于类别:[生物技術研究所] 期刊論文

文件中的档案:

档案 大小格式浏览次数
2020700310025.pdf7KbAdobe PDF661检视/开启


在NCUEIR中所有的数据项都受到原著作权保护.

 

DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈