National Changhua University of Education Institutional Repository : Item 987654321/11930

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NCUEIR > College of Engineering > Department and Graduate Institute of Electronic Engineering > Periodical Articles > Item 987654321/11930

Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/11930

Title:	Two-photon Fluorescence Correlation Spectroscopy through a Dual-Clad Optical Fiber
Authors:	Chang, Yu-Chung;Ye, Jing-Yong;Thomas, Thommey;Chen, Yi;Baker, James R.;Norris, Theodore B.
Contributors:	電機工程學系
Date:	2008
Issue Date:	2012-07-03T01:48:29Z
Publisher:	Optical Society of America
Abstract:	We report on the utilization of a dual-clad optical fiber for twophoton excited fluorescence correlation spectroscopy (FCS). High excitation efficiency is obtained by sending prechirped ultrafast pulses through the single-mode core of the fiber, while the fluorescence collection efficiency is enhanced because of the larger numerical aperture of the inner cladding. We show that the utilization of a dual-clad fiber is critical for ultrasensitive twophoton fluorescence detection. Our system has the ability to detect fluorescent nanospheres as small as 12 nm in radius. Quantum dots of radius 7 nm are also measured and show excellent signal to noise ratio. The particle sizes obtained from the fiber FCS system were confirmed by measurements using a commercial dynamic light scattering (DLS) system.
Relation:	Optics Express, 16(17): 12640-12649
Appears in Collections:	[Department and Graduate Institute of Electronic Engineering] Periodical Articles

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