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NCUEIR > College of Engineering > Department and Graduate Institute of Electronic Engineering > Proceedings > Item 987654321/11948

Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/11948

Title:	Quantification of Dentrimer Nanoparticle Targeting on Tumor Cells by Two-photon Excitation Fluorescence through a Dual-Clad Optical Fiber
Authors:	Chang, Yu-Chung;Thommey P. Thomas;Ye, Jing-Yong;Alina Kotlyar;Zhengyi Cao;Istvan J. Majoros;James R. Baker;Jr.;Theodore B. Norris
Contributors:	電機工程學系
Date:	2008-03
Issue Date:	2012-07-03T01:50:11Z
Publisher:	Optical Society of America
Abstract:	We report the use of a dual-clad optical fiber to conduct quantitative two-photon excited fluorescence measurements in vitro and in vivo inside tumors. The ability to detect nanomolar concentrations of tumor cell targeting nanoparticles with this dual-clad fiber scheme is confirmed. The results indicate that this technique is an appropriate tool to quantify low concentrations of targeted fluorescence probes in vivo in deep tissue.
Relation:	Biomedical Optics Topical Meeting(BIOMED), March 16, 2008
Appears in Collections:	[Department and Graduate Institute of Electronic Engineering] Proceedings

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