National Changhua University of Education Institutional Repository : Item 987654321/11948
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题名: Quantification of Dentrimer Nanoparticle Targeting on Tumor Cells by Two-photon Excitation Fluorescence through a Dual-Clad Optical Fiber
作者: Chang, Yu-Chung;Thommey P. Thomas;Ye, Jing-Yong;Alina Kotlyar;Zhengyi Cao;Istvan J. Majoros;James R. Baker;Jr.;Theodore B. Norris
贡献者: 電機工程學系
日期: 2008-03
上传时间: 2012-07-03T01:50:11Z
出版者: Optical Society of America
摘要: We report the use of a dual-clad optical fiber to conduct quantitative two-photon excited fluorescence measurements in vitro and in vivo inside tumors. The ability to detect nanomolar concentrations of tumor cell targeting nanoparticles with this dual-clad fiber scheme is confirmed. The results indicate that this technique is an appropriate tool to quantify low concentrations of targeted fluorescence probes in vivo in deep tissue.
關聯: Biomedical Optics Topical Meeting(BIOMED), March 16, 2008
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