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题名: Structural Characteristics and Antioxidative Capability of The Soluble Polysaccharides Present in Dictyophora indusiata (Vent. Ex Pers.) Fish Phallaceae
作者: Ker, Yaw-Bee;Chen, Kuan-Chou;Peng, Chiung-Chi;Hsieh, Chiu-Lan;Peng, Robert Y.
贡献者: 生物技術研究所
日期: 2010-05
上传时间: 2012-08-07T07:00:06Z
出版者: Hindawi Publishing Corporation
摘要: Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-S¯un, the bamboo fungi) has been used as a medicinal
mushroom to treat many inflammatory, gastric and neural diseases since 618AD in China. We hypothesize that the soluble
polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the
antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing
and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically
precipitated riboglucan from 2% NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44%
w/w, their molecular weight (MW) ranged within 801–4656 kDa. D3, having the smallest MW 801 kDa, exhibited the most
potent scavenging effect against the α,α-diphenyl-β-picrylhydrazyl, •OH−, and •O2− radicals, yielding IC50 values 0.11, 1.02 and
0.64 mgmL−1, respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not
entirely, to its soluble polysaccharide type regarding the MWand monosaccharide profiles.
關聯: Evidence-Based Complementary and Alternative Medicine eCAM Advance Access published May 9, 2010
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