Loading...
|
Please use this identifier to cite or link to this item:
http://ir.ncue.edu.tw/ir/handle/987654321/14958
|
Title: | Total Synthesis of (�)-camphorataimides and (�)-himanimides by NaBH4/Ni(OAc)2 or Zn/AcOH Stereoselective Reduction |
Authors: | Chang, C. F.;Lai, Z. C.;Lee, Yean-Jang |
Contributors: | 化學系 |
Date: | 2008-05
|
Issue Date: | 2012-12-10T02:51:51Z
|
Publisher: | Elsevier |
Abstract: | Maleic anhydride 1 of Antrodia camphorate, which can be isolated from Chinese herbal medicine, is achieved in which the longest linear sequence is only five steps, in 40% overall yield from commercially available succinic anhydride. The crucial antrodimides 3 and 2 can be readily transformed by the chemoselective reduction with Zn/AcOH and NaBH4/Ni(OAc)2·4H2O to afford the naturally occurring camphorataimides, 4 and 5, in high yields as well, respectively. This synthetic strategy can also be modified to give access to a variety of different maleic acid derivatives, himanimides 6–8. |
Relation: | Tetrahedron, 64(19): 4347-4353 |
Appears in Collections: | [化學系] 期刊論文
|
Files in This Item:
File |
Size | Format | |
index.html | 0Kb | HTML | 476 | View/Open |
|
All items in NCUEIR are protected by copyright, with all rights reserved.
|