National Changhua University of Education Institutional Repository : Item 987654321/14959
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 6507/11669
Visitors : 29995515      Online Users : 309
RC Version 3.2 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Adv. Search

Please use this identifier to cite or link to this item:

Title: Total Synthesis of Demethylwedelolactone and Wedelolactone by Cu-mediated/Pd(0)-catalysis and Oxidative-cyclization
Authors: Chang, C. F.;Yang, L. Y.;Chang, S. W.;Fang Y. T.;Lee, Yean-Jang
Contributors: 化學系
Date: 2008-04
Issue Date: 2012-12-10T02:51:52Z
Publisher: Elsevier
Abstract: Hedysarimcoumestan B, which can be isolated from Chinese herbal medicine, is achieved, in which the longest linear sequence is only eight steps, in 50% overall yield from commercially available phloroglucinol. The key transformations in the synthesis are Cu-mediated/Pd(0)-catalysis and I2/pyridine oxidative-cyclization reactions. This synthetic strategy can be applied to give access to the demethylwedelolactone (4) and wedelolactone (5), which were afforded from commercially available phloroglucinol in high 38 and 33% yields, respectively.
Relation: Tetrahedron, 64(17): 3661-3666
Appears in Collections:[Department of Chemistry] Periodical Articles

Files in This Item:

File SizeFormat

All items in NCUEIR are protected by copyright, with all rights reserved.


DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback