National Changhua University of Education Institutional Repository : Item 987654321/15028
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Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/15028

Title: Polyhydroxylated Indolines and Oxindoles from C-Glycosides via Sequential Henry Reaction, Michael Addition, and Reductive Amination/Amidation
Authors: Zou, Wei;Wu, An-Tai;Bhasin, Milan;Sandbhor, Mahendra;Wu, Shih-Hsiung
Contributors: 化學系
Date: 2007-03
Issue Date: 2013-01-07T01:47:47Z
Publisher: American Chemical Society
Abstract: 6-Nitro-2‘-carbonyl-C-glycofuranosides synthesized via Henry reaction from 1-C-allyl 5-aldo-C-glycoside underwent an intramolecular Michael addition to afford nitrocyclohexanol derivatives in good to excellent yield. Reduction of the nitro group followed by intramolecular amination with ketone and aldehyde and amidation with ester produced indoline and oxindole derivatives, respectively, in excellent yield.
Relation: J. Org. Chem., 72(7): 2686-2689
Appears in Collections:[Department of Chemistry] Periodical Articles

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