Loading...
|
Please use this identifier to cite or link to this item:
http://ir.ncue.edu.tw/ir/handle/987654321/16776
|
| Title: | Curcumin Affects Development of Zebrafish Embryo |
| Authors: | Wu, Jheng-Yu;Lin, Chin-Yi;Lin, Tien-Wei;Ken, Chuian-Fu;Wen, Yu-Der |
| Contributors: | 生物學系 |
| Keywords: | Curcumin;Embryotoxicity;Zebrafish |
| Date: | 2007
|
| Issue Date: | 2013-06-05T08:48:17Z
|
| Publisher: | Pharmaceutical Society of Japan |
| Abstract: | Embryotoxic and teratogenic effects of curcumin on the development of zebrafish embryo were investi-gated in this study. The LD50 values of curcumin (24-h incubation) were estimated at 7.5 μM and 5 μM for embryos and larvae, respectively. The developmental defects caused by curcumin treatments include bent or hook-like tails, spinal column curving, edema in pericardial sac, retarded yolk sac resorption, and shorter body length. In curcumin-treated larvae, fluorescence signals of curcumin were found in edamae sac and some skin cells. Together, these results indicate that zebrafish are suitable model organisms to study the toxic effects of curcumin. |
| Relation: | Biological & Pharmaceutical Bulletin, 30(7): 1336-1339 |
| Appears in Collections: | [生物學系] 期刊論文
|
Files in This Item:
| File |
Size | Format | |
|---|
| index.html | 0Kb | HTML | 516 | View/Open |
|
All items in NCUEIR are protected by copyright, with all rights reserved.
|
