English  |  正體中文  |  简体中文  |  Items with full text/Total items : 6487/11649
Visitors : 28626647      Online Users : 349
RC Version 3.2 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Adv. Search

Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/16776

Title: Curcumin Affects Development of Zebrafish Embryo
Authors: Wu, Jheng-Yu;Lin, Chin-Yi;Lin, Tien-Wei;Ken, Chuian-Fu;Wen, Yu-Der
Contributors: 生物學系
Keywords: Curcumin;Embryotoxicity;Zebrafish
Date: 2007
Issue Date: 2013-06-05T08:48:17Z
Publisher: Pharmaceutical Society of Japan
Abstract: Embryotoxic and teratogenic effects of curcumin on the development of zebrafish embryo were investi-gated in this study. The LD50 values of curcumin (24-h incubation) were estimated at 7.5 μM and 5 μM for embryos and larvae, respectively. The developmental defects caused by curcumin treatments include bent or hook-like tails, spinal column curving, edema in pericardial sac, retarded yolk sac resorption, and shorter body length. In curcumin-treated larvae, fluorescence signals of curcumin were found in edamae sac and some skin cells. Together, these results indicate that zebrafish are suitable model organisms to study the toxic effects of curcumin.
Relation: Biological & Pharmaceutical Bulletin, 30(7): 1336-1339
Appears in Collections:[生物學系] 期刊論文

Files in This Item:

File SizeFormat

All items in NCUEIR are protected by copyright, with all rights reserved.


DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback