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Title: A Method for the Regioselective Synthesis of 1-alkyl-1H-indazoles
Authors: Liu, Han-Jun;Hung, Shiang-Fu;Chen, Chuan-Lin;Lin, Mei-Huey
Contributors: 化學系
Keywords: 2-Halobenzonitriles;Deamination;Indazoles;N-Alkylhydrazines;Regioselective
Date: 2013-05
Issue Date: 2013-06-06T02:33:46Z
Publisher: Elsevier
Abstract: A method for the regioselective synthesis of 3-unsubstituted 1-alkyl-1H-indazoles, starting with 2-halobenzonitriles and N-alkylhydrazines, is described. The two-step reaction pathway proceeds through the intermediacy of 1-alkyl-3-amino-1H-indazoles followed by reductive deamination.
Relation: Tetrahedron, 69(19): 3907-3912
Appears in Collections:[Department of Chemistry] Periodical Articles

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