National Changhua University of Education Institutional Repository : Item 987654321/1834

English | 正體中文 | 简体中文 | Items with full text/Total items : 6507/11669
Visitors : 30417796 Online Users : 375

RC Version 3.2 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.

Scope Adv. Search

Login ‧ Upload ‧ Help ‧ About ‧ Administer

NCUEIR > College of Science > Department of Biology > Periodical Articles > Item 987654321/1834

Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/1834

Title:	Curcumin Affects Development of Zebrafish Embryo
Authors:	Jheng-Yu Wu;Chin-Yi LIN;Tien-Wei LIN;Chuian-Fu KEN;Yu-Der WEN
Contributors:	生物學系
Date:	2007-07
Issue Date:	2010-11-15T07:01:17Z
Abstract:	Embryotoxic and teratogenic effects of curcumin on the development of zebrafish embryo were investigated in this study. The LD50 values of curcumin (24-h incubation) were estimated at 7.5 μM and 5 μM for embryos and larvae, respectively. The developmental defects caused by curcumin treatments include bent or hook-like tails, spinal column curving, edema in pericardial sac, retarded yolk sac resorption, and shorter body length. In curcumin-treated larvae, fluorescence signals of curcumin were found in edamae sac and some skin cells. Together, these results indicate that zebrafish are suitable model organisms to study the toxic effects of curcumin.
Relation:	Biological & Pharmaceutical Bulletin, 30(7): 1336-9. (SCI)
Appears in Collections:	[Department of Biology] Periodical Articles

Files in This Item:

There are no files associated with this item.