資料載入中.....
|
請使用永久網址來引用或連結此文件:
http://ir.ncue.edu.tw/ir/handle/987654321/9763
|
| 題名: | Effect of Ethanol Extracts of Three Chinese Medicinal Plants with Anti-diarrheal Properties on Ion Transport of the Rat Intestinal Epithelia |
| 作者: | Tsai, Jong-Chang;Tsai, S.;Chang, W.C. |
| 貢獻者: | 應用運動科學所 |
| 關鍵詞: | Chinese medicinal plant, ion transport, intestinal epithelia, anti-diarrhea, |
| 日期: | 2004-02
|
| 上傳時間: | 2012-04-20T02:22:33Z
|
| 出版者: | The Japanese Pharmacological Society |
| 摘要: | Effects of ethanol extracts of three Chinese medicinal plants, namely, Qinpi (Fraxini cortex), Kushen (Sophora flavescens, AITON), and Huanglian (Coptis teeta, WALLICH), on ion transport of the rat intestinal epithelia were determined in this study. Rat intestinal epithelia mounted in an Ussing chamber attached to a voltage/current clamp were used for measuring changes in the short circuit current across the epithelia. Activation of the intestinal epithelia by serosal administration of 5 microM forskolin resulted in an increase in basal short circuit current. The ethanol extracts of each of the three plants partially reduced the current stimulated by forskolin. In the following experiments, ouabain and bumetanide were added prior to adding the ethanol extract of these plants for revealing their effect on Na(+) and Cl(-) movement. The results suggest that the ethanol extract of the Qinpi would affect Cl(-) transport. On the contrary, the ethanol extract of Kushen would affect Na(+) transport rather than Cl(-) movement. This study provides evidences that reveal the pharmacological mechanism of the Chinese plants with anti-diarrheal properties. |
| 關聯: | Journal of Pharmacological Sciences, 94: 60-66 |
| 顯示於類別: | [應用運動科學研究所] 期刊論文
|
文件中的檔案:
| 檔案 |
大小 | 格式 | 瀏覽次數 |
|---|
| 2070100410003.pdf | 248Kb | Adobe PDF | 1335 | 檢視/開啟 |
|
在NCUEIR中所有的資料項目都受到原著作權保護.
|
