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NCUEIR > College of Science > biotech > Proceedings > Item 987654321/13269

Please use this identifier to cite or link to this item: http://ir.ncue.edu.tw/ir/handle/987654321/13269

Title:	Structural Characteristics and Antioxidative Capability of The Soluble Polysaccharides Present in Dictyophora indusiata (Vent. Ex Pers.) Fish Phallaceae
Authors:	Ker, Yaw-Bee;Chen, Kuan-Chou;Peng, Chiung-Chi;Hsieh, Chiu-Lan;Peng, Robert Y.
Contributors:	生物技術研究所
Date:	2010-05
Issue Date:	2012-08-07T07:00:06Z
Publisher:	Hindawi Publishing Corporation
Abstract:	Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-S¯un, the bamboo fungi) has been used as a medicinal mushroom to treat many inflammatory, gastric and neural diseases since 618AD in China. We hypothesize that the soluble polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically precipitated riboglucan from 2% NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44% w/w, their molecular weight (MW) ranged within 801–4656 kDa. D3, having the smallest MW 801 kDa, exhibited the most potent scavenging effect against the α,α-diphenyl-β-picrylhydrazyl, •OH−, and •O2− radicals, yielding IC50 values 0.11, 1.02 and 0.64 mgmL−1, respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not entirely, to its soluble polysaccharide type regarding the MWand monosaccharide profiles.
Relation:	Evidence-Based Complementary and Alternative Medicine eCAM Advance Access published May 9, 2010
Appears in Collections:	[biotech] Proceedings

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