National Changhua University of Education Institutional Repository : Item 987654321/14948
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題名: Synthesis of Caffeic Acid Esters as Antioxidants by Esterification via Acyl Chlorides
作者: Chen, W. K.;Liao, P. H.;Tsai, C. F.;Lee, Yean-Jang
貢獻者: 化學系
關鍵詞: Caffeic acid phenethyl ester;Antioxidant;Esterification
日期: 1999-08
上傳時間: 2012-12-10T02:51:26Z
出版者: 中國藥學會臺灣省分會
摘要: As part of our search for new compounds with improved antibiotic, antiviral, anti-inflammatory and tumor growth inhibition activities, we prepared some caffeic acid esters from commercially available caffeic acid. The rapid total synthesis of caffeic acid esters is described. Highlights of the synthesis include esterification with pyridine catalyst and thermal esterification of acyl chlorides and alcohols in nitrobenzene. Several strategies to accomplish this goal are provided. Finally, CAPE (caffeic acid phenylethyl ester) quenched the free radicals as a phenolic antioxidant.
關聯: The Chinese Pharmaceutical Journal, 51(4): 271-278
顯示於類別:[化學系] 期刊論文

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